Kvalme er en ubehagsfornemmelse i mellomgulv og mage, som ofte er fulgt av en fileølelse av at en vil kaste opp.GraviditetSkal ikke brukes. Langvarig bruk less than svangerskapet kan gi fysisk avhengighet og neonatalt abstinenssyndrom. Skal ikke brukes i andre fødselsfase eller ved for tidlig nedkomst, da det kan gi neonatal respirasjonsdepresjon

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